A Family trip to the city of Sin. A comedy. Along the way, they see the weirdness. Perhaps they learn to love each other more, perhaps they learn to accept each other. Perhaps its a movie of the parents looking for their almost adult daughter who wanders off into the crowd.
Perhaps they find some sort of solace in the decorated Catholic cathedral in the middle of town.
I dunno, but if someone can find a couple of million dollars to throw at this thing, I wouldn't mind filming it in the French Quarter.